This book addresses an extremely prevalent medical problem: low back pain. It is not a general anatomy book, but it relates specifically to the lumbosacral spine, encompassing anatomy, histology, histopathology, and imaging all in one volume. For students, the text incrementally introduces them to lumbosacral anatomy terms and scientific knowledge by using photographs of gross and histological sections of the spine, as well as schematic drawings and images, in preparation for clinical practice. It answers many questions about the pathogenesis of low back pain, helpful for clinicians, both for treatment decisions and for counselling patients.