Stereo EEG has revolutionized the way invasive EEG explorations are performed, facilitating the assessment of more complex cases with increased precision, a lower surgical risk, and better patient outcomes. A Practical Approach to Stereo EEG is the first dedicated reference on stereoelectroencephalography written for trainees, physicians, and technologists involved in invasive EEG evaluation and monitoring. This go-to resource provides a practical overview of the concepts, methodology, technical requirements, and implantation strategies for common and uncommon surgical epilepsies amenable to stereo EEG. Including over three hundred detailed figures, anatomical drawings, and MRI correlations, this guidebook is an indispensable tool for anyone training, practicing, and teaching in the field.