This much praised and widely used reference manual on has been extensively revised and expanded to cover the entire field of anatomic pathology. The Fourth Edition features the incorporation of full-color images in the text with updates of new diagnostic and prognostic information. New classifications and numerous new entities and histologic variants for each organ site will be fully incorporate in each individual chapter (Part II Organ Systems). Useful immunostaining biomarkers and emerging molecular targets and relevant molecular findings that have emerged from recent genomic studies are incorporated in each chapter.